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Nucleophile responsive charge-reversing polycations for pDNA transfection

Polycationic carriers promise low cost and scalable gene therapy treatments, however inefficient intracellular unpacking of the genetic cargo has limited transfection efficiency. Charge-reversing polycations, which transition from cationic to neutral or negative charge, can offer targeted intracellu...

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Detalles Bibliográficos
Autores principales:	Lewis, Reece W., Muralidharan, Aswin, Klemm, Benjamin, Boukany, Pouyan E., Eelkema, Rienk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071491/ https://www.ncbi.nlm.nih.gov/pubmed/37033743 http://dx.doi.org/10.1039/d3py00075c

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