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A novel small molecule, AS1, reverses the negative hedonic valence of noxious stimuli

BACKGROUND: Pain is the primary reason people seek medical care, with chronic pain affecting ~ 20% of people in the USA. However, many existing analgesics are ineffective in treating chronic pain, while others (e.g., opioids) have undesirable side effects. Here, we describe the screening of a small...

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Detalles Bibliográficos
Autores principales: Esancy, Kali, Conceicao, Lais L., Curtright, Andrew, Tran, Thanh, Condon, Logan, Lecamp, Bryce, Dhaka, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071644/
https://www.ncbi.nlm.nih.gov/pubmed/37013580
http://dx.doi.org/10.1186/s12915-023-01573-7