APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired elderly

BACKGROUND: Neuroinflammation, characterized by increased reactivity of microglia and astrocytes in the brain, is known to be present at various stages of the Alzheimer’s disease (AD) continuum. However, its presence and relationship with amyloid pathology in cognitively normal at-risk individuals i...

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Detalles Bibliográficos
Autores principales: Snellman, Anniina, Ekblad, Laura L., Tuisku, Jouni, Koivumäki, Mikko, Ashton, Nicholas J., Lantero-Rodriguez, Juan, Karikari, Thomas K., Helin, Semi, Bucci, Marco, Löyttyniemi, Eliisa, Parkkola, Riitta, Karrasch, Mira, Schöll, Michael, Zetterberg, Henrik, Blennow, Kaj, Rinne, Juha O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071691/
https://www.ncbi.nlm.nih.gov/pubmed/37016464
http://dx.doi.org/10.1186/s13195-023-01209-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071691/
https://www.ncbi.nlm.nih.gov/pubmed/37016464
http://dx.doi.org/10.1186/s13195-023-01209-6

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