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Crotonylation of GAPDH regulates human embryonic stem cell endodermal lineage differentiation and metabolic switch
BACKGROUND: Post-translational modifications of proteins are crucial to the regulation of their activity and function. As a newly discovered acylation modification, crotonylation of non-histone proteins remains largely unexplored, particularly in human embryonic stem cells (hESCs). METHODS: We inves...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071711/ https://www.ncbi.nlm.nih.gov/pubmed/37013624 http://dx.doi.org/10.1186/s13287-023-03290-y |