IFN-γ blockade after genetic inhibition of PD-1 aggravates skeletal muscle damage and impairs skeletal muscle regeneration

BACKGROUND: Innate immune responses play essential roles in skeletal muscle recovery after injury. Programmed cell death protein 1 (PD-1) contributes to skeletal muscle regeneration by promoting macrophage proinflammatory to anti-inflammatory phenotype transition. Interferon (IFN)-γ induces proinfla...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhuang, Shuzhao, Russell, Aaron, Guo, Yifan, Xu, Yingying, Xiao, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071770/
https://www.ncbi.nlm.nih.gov/pubmed/37016287
http://dx.doi.org/10.1186/s11658-023-00439-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071770/
https://www.ncbi.nlm.nih.gov/pubmed/37016287
http://dx.doi.org/10.1186/s11658-023-00439-8

Ejemplares similares