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IFN-γ blockade after genetic inhibition of PD-1 aggravates skeletal muscle damage and impairs skeletal muscle regeneration

BACKGROUND: Innate immune responses play essential roles in skeletal muscle recovery after injury. Programmed cell death protein 1 (PD-1) contributes to skeletal muscle regeneration by promoting macrophage proinflammatory to anti-inflammatory phenotype transition. Interferon (IFN)-γ induces proinfla...

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Detalles Bibliográficos
Autores principales:	Zhuang, Shuzhao, Russell, Aaron, Guo, Yifan, Xu, Yingying, Xiao, Weihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071770/ https://www.ncbi.nlm.nih.gov/pubmed/37016287 http://dx.doi.org/10.1186/s11658-023-00439-8

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