Preclinical Evaluation of (89)Zr-Desferrioxamine-Bexmarilimab, a Humanized Antibody Against Common Lymphatic Endothelial and Vascular Endothelial Receptor-1, in a Rabbit Model of Renal Fibrosis

Bexmarilimab is a new humanized monoclonal antibody against common lymphatic endothelial and vascular endothelial receptor-1 (CLEVER-1) and is in clinical trials for macrophage-guided cancer immunotherapy. In addition being associated with cancer, CLEVER-1 is also associated with fibrosis. To facili...

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Detalles Bibliográficos
Autores principales: Moisio, Olli, Virta, Jenni, Yatkin, Emrah, Liljenbäck, Heidi, Palani, Senthil, Viitanen, Riikka, Miner, Maxwell W.G., Oikonen, Vesa, Tolvanen, Tuula, Vugts, Danielle J., Taimen, Pekka, Li, Xiang-Guo, Hollmén, Maija, Jalkanen, Sirpa, Roivainen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2023
Materias:
Basic Science Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071790/
https://www.ncbi.nlm.nih.gov/pubmed/36302655
http://dx.doi.org/10.2967/jnumed.122.264725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071790/
https://www.ncbi.nlm.nih.gov/pubmed/36302655
http://dx.doi.org/10.2967/jnumed.122.264725

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