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Preclinical Evaluation of (89)Zr-Desferrioxamine-Bexmarilimab, a Humanized Antibody Against Common Lymphatic Endothelial and Vascular Endothelial Receptor-1, in a Rabbit Model of Renal Fibrosis
Bexmarilimab is a new humanized monoclonal antibody against common lymphatic endothelial and vascular endothelial receptor-1 (CLEVER-1) and is in clinical trials for macrophage-guided cancer immunotherapy. In addition being associated with cancer, CLEVER-1 is also associated with fibrosis. To facili...
Autores principales: | Moisio, Olli, Virta, Jenni, Yatkin, Emrah, Liljenbäck, Heidi, Palani, Senthil, Viitanen, Riikka, Miner, Maxwell W.G., Oikonen, Vesa, Tolvanen, Tuula, Vugts, Danielle J., Taimen, Pekka, Li, Xiang-Guo, Hollmén, Maija, Jalkanen, Sirpa, Roivainen, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society of Nuclear Medicine
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071790/ https://www.ncbi.nlm.nih.gov/pubmed/36302655 http://dx.doi.org/10.2967/jnumed.122.264725 |
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