Cargando…

A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle

Proper cellular proteostasis, essential for viability, requires a network of chaperones and cochaperones. ATP-dependent chaperonin TRiC/CCT partners with cochaperones prefoldin (PFD) and phosducin-like proteins (PhLPs) to facilitate the folding of essential eukaryotic proteins. Using cryoEM and bioc...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Junsun, Kim, Hyunmin, Gestaut, Daniel, Lim, Seyeon, Leitner, Alexander, Frydman, Judith, Roh, Soung-Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071816/
https://www.ncbi.nlm.nih.gov/pubmed/37016670
http://dx.doi.org/10.1101/2023.03.25.534239