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Targeting Mutated p53: Naivete and Enthusiasm to Attempt the Impossible
Tumor suppressor TP53 is an important gene in human cancer because it is mutated in the majority of tumors, leading to loss-of-function or gain-of-function phenotypes. Mutated TP53 acts like an oncogene, driving cancer progression and causing poor patient outcomes. The role of mutated p53 in cancer...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Association for Cancer Research
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071817/ https://www.ncbi.nlm.nih.gov/pubmed/37014041 http://dx.doi.org/10.1158/0008-5472.CAN-22-0995 |