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Transport of Designed Ankyrin Repeat Proteins through reconstituted human bronchial epithelia and protection against SARS-CoV-2

Clinical studies have proven antiviral effectiveness of treatment with a Designed Ankyrin Repeat Protein (DARPin) specific against the spike protein of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). More information on transport mechanisms and efficiency to the site of action is...

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Detalles Bibliográficos
Autores principales: Künzi, Lisa, Ryter, Sarah, Cornelius, Andreas, Leni, Zaira, Baumlin, Nathalie, Salathe, Matthias, Walser, Marcel, Engler, Olivier, Geiser, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072008/
https://www.ncbi.nlm.nih.gov/pubmed/37016030
http://dx.doi.org/10.1038/s41598-023-32269-1