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Phenotypic and transcriptomic impact of expressing mammalian TET2 in the Drosophila melanogaster model

Ten-Eleven Translocation (TET) proteins have recently come to light as important epigenetic regulators conserved in multicellular organisms. TET knockdown studies in rodents have highlighted the critical role of these proteins for proper brain development and function. Mutations in mammalian mTET pr...

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Detalles Bibliográficos
Autores principales: Ismail, Joy N., Mantash, Sarah, Hallal, Mohammad, Jabado, Nada, Khoueiry, Pierre, Shirinian, Margret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072067/
https://www.ncbi.nlm.nih.gov/pubmed/36989121
http://dx.doi.org/10.1080/15592294.2023.2192375