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DNA methylome and transcriptome profiling reveal key electrophysiology and immune dysregulation in hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is the most common inherited heart disease. However, a detailed DNA methylation (DNAme) landscape has not yet been elucidated. Our study combined DNAme and transcriptome profiles for HCM myocardium and identify aberrant DNAme associated with altered myocardial funct...

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Detalles Bibliográficos
Autores principales: Li, Xiaoyan, Fan, Hailang, Song, Xiantao, Song, Bangrong, Liu, Wenxian, Dong, Ran, Zhang, Haikun, Guo, Shicheng, Liang, Hao, Schrodi, Steven J., Fu, Xuebin, Kaushal, Sunjay, Ren, Yanlong, Zhang, Dake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072074/
https://www.ncbi.nlm.nih.gov/pubmed/37005704
http://dx.doi.org/10.1080/15592294.2023.2195307