Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy

Tumor-associated macrophages (TAMs) are abundant in pancreatic ductal adenocarcinomas (PDACs). While TAMs are known to proliferate in cancer tissues, the impact of this on macrophage phenotype and disease progression is poorly understood. We showed that in PDAC, proliferation of TAMs could be driven...

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Detalles Bibliográficos
Autores principales: Zuo, Chong, Baer, John M., Knolhoff, Brett L., Belle, Jad I., Liu, Xiuting, Alarcon De La Lastra, Angela, Fu, Christina, Hogg, Graham D., Kingston, Natalie L., Breden, Marcus A., Dodhiawala, Paarth B., Zhou, Daniel Cui, Lander, Varintra E., James, C. Alston, Ding, Li, Lim, Kian-Huat, Fields, Ryan C., Hawkins, William G., Weber, Jason D., Zhao, Guoyan, DeNardo, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072222/
https://www.ncbi.nlm.nih.gov/pubmed/36951731
http://dx.doi.org/10.1084/jem.20212062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072222/
https://www.ncbi.nlm.nih.gov/pubmed/36951731
http://dx.doi.org/10.1084/jem.20212062

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