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Efficacy and Safety of Flexibly Dosed Esketamine Nasal Spray Plus a Newly Initiated Oral Antidepressant in Adult Patients with Treatment-Resistant Depression: A Randomized, Double-Blind, Multicenter, Active-Controlled Study Conducted in China and USA

PURPOSE: This Phase 3, multicenter study (NCT03434041) was conducted in primarily Chinese patients with treatment-resistant depression (TRD) to support the registration of esketamine nasal spray in China. PATIENTS AND METHODS: This randomized, double-blind, active-controlled study was conducted in C...

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Detalles Bibliográficos
Autores principales: Chen, Xu, Hou, Xuan, Bai, Daisy, Lane, Rosanne, Zhang, Chong, Canuso, Carla, Wang, Gang, Fu, Dong-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072270/
https://www.ncbi.nlm.nih.gov/pubmed/37025256
http://dx.doi.org/10.2147/NDT.S391096