Drosophila SPG12 ortholog, reticulon-like 1, governs presynaptic ER organization and Ca(2+) dynamics

Neuronal endoplasmic reticulum (ER) appears continuous throughout the cell. Its shape and continuity are influenced by ER-shaping proteins, mutations in which can cause distal axon degeneration in Hereditary Spastic Paraplegia (HSP). We therefore asked how loss of Rtnl1, a Drosophila ortholog of the...

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Detalles Bibliográficos
Autores principales: Pérez-Moreno, Juan José, Smith, Rebecca C., Oliva, Megan K., Gallo, Filomena, Ojha, Shainy, Müller, Karin H., O’Kane, Cahir J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072275/
https://www.ncbi.nlm.nih.gov/pubmed/36952540
http://dx.doi.org/10.1083/jcb.202112101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072275/
https://www.ncbi.nlm.nih.gov/pubmed/36952540
http://dx.doi.org/10.1083/jcb.202112101

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