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Rate thresholds in cell signaling have functional and phenotypic consequences in non-linear time-dependent environments

All cells employ signal transduction pathways to respond to physiologically relevant extracellular cytokines, stressors, nutrient levels, hormones, morphogens, and other stimuli that vary in concentration and rate in healthy and diseased states. A central unsolved fundamental question in cell signal...

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Detalles Bibliográficos
Autores principales: Thiemicke, Alexander, Neuert, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072286/
https://www.ncbi.nlm.nih.gov/pubmed/37025183
http://dx.doi.org/10.3389/fcell.2023.1124874