CHAC1 inactivation is effective to preserve muscle glutathione but is insufficient to protect against muscle wasting in cachexia

Muscle wasting is one of the main characteristics of cachexia associated with cancer and other chronic diseases and is often exacerbated by antineoplastic agents. Increased oxidative stress is associated with muscle wasting, along with depletion of glutathione, the most abundant endogenous antioxida...

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Detalles Bibliográficos
Autores principales: Li, Junjie, Lu, Mingjian, Ahn, Youngwook, Cao, Kevin, Pinkus, Cynthia A., Stansfield, John C., Wu, Zhidan, Zhang, Bei B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072464/
https://www.ncbi.nlm.nih.gov/pubmed/37014882
http://dx.doi.org/10.1371/journal.pone.0283806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072464/
https://www.ncbi.nlm.nih.gov/pubmed/37014882
http://dx.doi.org/10.1371/journal.pone.0283806

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