A seeding-based neuronal model of tau aggregation for use in drug discovery

Intracellular accumulation of tau protein is a hallmark of Alzheimer’s Disease and Progressive Supranuclear Palsy, as well as other neurodegenerative disorders collectively known as tauopathies. Despite our increasing understanding of the mechanisms leading to the initiation and progression of tau p...

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Detalles Bibliográficos
Autores principales: Amorim, Ines S., Challal, Sylvie, Cistarelli, Laetitia, Dorval, Thierry, Abjean, Laurene, Touzard, Manuelle, Arbez, Nicolas, François, Arnaud, Panayi, Fany, Jeggo, Ross, Cecon, Erika, Oishi, Atsuro, Dam, Julie, Jockers, Ralf, Machado, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072482/
https://www.ncbi.nlm.nih.gov/pubmed/37014877
http://dx.doi.org/10.1371/journal.pone.0283941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072482/
https://www.ncbi.nlm.nih.gov/pubmed/37014877
http://dx.doi.org/10.1371/journal.pone.0283941

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