A hydrogel model of the human blood-brain barrier using differentiated stem cells

An in vitro model of the human blood-brain barrier was developed, based on a collagen hydrogel containing astrocytes, overlaid with a monolayer of endothelium, differentiated from human induced pluripotent stem cells (hiPSCs). The model was set up in transwell filters allowing sampling from apical a...

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Detalles Bibliográficos
Autores principales: Singh, Nandita Rahatekar, Gromnicova, Radka, Brachner, Andreas, Kraev, Igor, Romero, Ignacio A., Neuhaus, Winfried, Male, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072488/
https://www.ncbi.nlm.nih.gov/pubmed/37014916
http://dx.doi.org/10.1371/journal.pone.0283954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10072488/
https://www.ncbi.nlm.nih.gov/pubmed/37014916
http://dx.doi.org/10.1371/journal.pone.0283954

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