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Mapping the protein binding site of the (pro)renin receptor using in silico 3D structural analysis

We have previously reported that monoclonal antibodies against the (pro)renin receptor [(P)RR] can reduce the Wnt/β-catenin-dependent development of pancreatic ductal adenocarcinoma (PDAC), the most common pancreatic cancer. Antibodies against two (P)RR regions (residues 47–60 and 200–213) located i...

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Detalles Bibliográficos
Autores principales: Ebihara, Akio, Sugihara, Daiki, Matsuyama, Makoto, Suzuki-Nakagawa, Chiharu, Nabi, A. H. M. Nurun, Nakagawa, Tsutomu, Nishiyama, Akira, Suzuki, Fumiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073018/
https://www.ncbi.nlm.nih.gov/pubmed/36481966
http://dx.doi.org/10.1038/s41440-022-01094-w