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Mapping the protein binding site of the (pro)renin receptor using in silico 3D structural analysis
We have previously reported that monoclonal antibodies against the (pro)renin receptor [(P)RR] can reduce the Wnt/β-catenin-dependent development of pancreatic ductal adenocarcinoma (PDAC), the most common pancreatic cancer. Antibodies against two (P)RR regions (residues 47–60 and 200–213) located i...
Autores principales: | Ebihara, Akio, Sugihara, Daiki, Matsuyama, Makoto, Suzuki-Nakagawa, Chiharu, Nabi, A. H. M. Nurun, Nakagawa, Tsutomu, Nishiyama, Akira, Suzuki, Fumiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073018/ https://www.ncbi.nlm.nih.gov/pubmed/36481966 http://dx.doi.org/10.1038/s41440-022-01094-w |
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