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Toxoplasma gondii-derived antigen modifies tumor microenvironment of Ehrlich solid carcinoma murine model and enhances immunotherapeutic activity of cyclophosphamide

Pathogen-based cancer vaccine is a promising immunotherapeutic weapon to stimulate cancer immunosuppressive state. Toxoplasma gondii is a potent immunostimulant, and low-dose infection was linked to cancer resistance. Our goal was to evaluate the therapeutic antineoplastic activity of autoclaved Tox...

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Detalles Bibliográficos
Autores principales: Ismail, Cherine A., Eissa, Maha M., Gaafar, Maha R., Younis, Layla K., El Skhawy, Nahla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073061/
https://www.ncbi.nlm.nih.gov/pubmed/37014499
http://dx.doi.org/10.1007/s12032-023-01994-y