Necrocide 1 mediates necrotic cell death and immunogenic response in human cancer cells

Many anticancer agents induce apoptosis, mitotic catastrophe or cellular senescence. Here, we report the functional characterization of an experimental inducer of tumor necrosis factor (TNF)-independent necrosis, necrocide-1 (NC1). NC1 (but not its stereoisomer) killed a panel of human cancer cells...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Trojel-Hansen, Christina, Wang, Jianghuang, Zhang, Zili, Wang, Xing, Qiao, Yuhui, Jiao, Huike, Michaud, Mickaël, Kepp, Oliver, Jäättelä, Marja, Kroemer, Guido, Zhong, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073102/
https://www.ncbi.nlm.nih.gov/pubmed/37015922
http://dx.doi.org/10.1038/s41419-023-05740-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073102/
https://www.ncbi.nlm.nih.gov/pubmed/37015922
http://dx.doi.org/10.1038/s41419-023-05740-0

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