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FHL2 deficiency impairs follicular development and fertility by attenuating EGF/EGFR/YAP signaling in ovarian granulosa cells

Female subfertility is an increasing reproductive issue worldwide, which is partially related to abnormal ovarian follicular development. Granulosa cells (GCs), by providing the necessary physical support and microenvironment for follicular development, play critical roles in maintaining female fert...

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Detalles Bibliográficos
Autores principales: Wang, Chen, Sun, Hui, Davis, John S., Wang, Xiaojie, Huo, Lijun, Sun, Nan, Huang, Qianzhi, Lv, Xiangmin, Wang, Cheng, He, Chunbo, He, Changjiu, Zhou, Yang, Wu, Jiyun, Yang, Liguo, Hua, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073124/
https://www.ncbi.nlm.nih.gov/pubmed/37015904
http://dx.doi.org/10.1038/s41419-023-05759-3