Levosimendan inhibits disulfide tau oligomerization and ameliorates tau pathology in Tau(P301L)-BiFC mice

Tau oligomers play critical roles in tau pathology and are responsible for neuronal cell death and transmitting the disease in the brain. Accordingly, preventing tau oligomerization has become an important therapeutic strategy to treat tauopathies, including Alzheimer’s disease. However, progress ha...

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Detalles Bibliográficos
Autores principales: Lim, Sungsu, Shin, Seulgi, Sung, Yoonsik, Lee, Ha Eun, Kim, Kyu Hyeon, Song, Ji Yeon, Lee, Gwan-Ho, Aziz, Hira, Lukianenko, Nataliia, Kang, Dong Min, Boesen, Nicolette, Jeong, Hyeanjeong, Abdildinova, Aizhan, Lee, Junghee, Yu, Byung-Yong, Lim, Sang Min, Lee, Jun-Seok, Ryu, Hoon, Pae, Ae Nim, Kim, Yun Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073126/
https://www.ncbi.nlm.nih.gov/pubmed/36914856
http://dx.doi.org/10.1038/s12276-023-00959-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073126/
https://www.ncbi.nlm.nih.gov/pubmed/36914856
http://dx.doi.org/10.1038/s12276-023-00959-5

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