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Single-cell sequencing reveals that endothelial cells, EndMT cells and mural cells contribute to the pathogenesis of cavernous malformations

Cavernous malformations (CMs) invading the central nervous system occur in ~0.16–0.4% of the general population, often resulting in hemorrhages and focal neurological deficits. Further understanding of disease mechanisms and therapeutic strategies requires a deeper knowledge of CMs in humans. Herein...

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Detalles Bibliográficos
Autores principales: Ren, Jian, Xiao, Xiao, Li, Ruofei, Lv, Cheng, Zhang, Yu, Wang, Leiming, Hong, Tao, Zhang, Hongqi, Wang, Yibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073145/
https://www.ncbi.nlm.nih.gov/pubmed/36914857
http://dx.doi.org/10.1038/s12276-023-00962-w