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Increased retinoic acid signaling decreases lung metastasis in salivary adenoid cystic carcinoma by inhibiting the noncanonical Notch1 pathway

MYB-NFIB fusion and NOTCH1 mutation are common hallmark genetic events in salivary gland adenoid cystic carcinoma (SACC). However, abnormal expression of MYB and NOTCH1 is also observed in patients without MYB-NFIB fusion and NOTCH1 mutation. Here, we explore in-depth the molecular mechanisms of lun...

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Detalles Bibliográficos
Autores principales: Zhou, Meng-jiao, Yang, Jia-jie, Ma, Ting-yao, Feng, Ge-xuan, Wang, Xue-lian, Wang, Li-Yong, Ge, Yu-ze, Gao, Ran, Liu, Hong-liang, Shan, Lin, Kong, Lu, Chen, Xiao-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073150/
https://www.ncbi.nlm.nih.gov/pubmed/36879115
http://dx.doi.org/10.1038/s12276-023-00957-7