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The roles of N6-methyladenosine and its target regulatory noncoding RNAs in tumors: classification, mechanisms, and potential therapeutic implications

N6-methyladenosine (m6A) is one of the epigenetic modifications of RNA. The addition of this chemical mark to RNA molecules regulates gene expression by affecting the fate of the RNA molecules. This posttranscriptional RNA modification is reversible and regulated by methyltransferase “writers” and d...

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Detalles Bibliográficos
Autores principales: Liu, Ziying, Gao, Lei, Cheng, Long, Lv, Gaoyuan, Sun, Bei, Wang, Gang, Tang, Qiushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073155/
https://www.ncbi.nlm.nih.gov/pubmed/36854773
http://dx.doi.org/10.1038/s12276-023-00944-y