Inhibition of mitochondrial phosphate carrier prevents high phosphate-induced superoxide generation and vascular calcification

Vascular calcification is a serious complication of hyperphosphatemia that causes cardiovascular morbidity and mortality. Previous studies have reported that plasmalemmal phosphate (Pi) transporters, such as PiT-1/2, mediate depolarization, Ca(2+) influx, oxidative stress, and calcific changes in va...

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Detalles Bibliográficos
Autores principales: Thi Nguyen, Nhung, Thi Nguyen, Tuyet, Nguyen, Ha Thu, Lee, Ji-Min, Kim, Min-Ji, Qi, Xu-Feng, Cha, Seung-Kuy, Lee, In-Kyu, Park, Kyu-Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073177/
https://www.ncbi.nlm.nih.gov/pubmed/36854772
http://dx.doi.org/10.1038/s12276-023-00950-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073177/
https://www.ncbi.nlm.nih.gov/pubmed/36854772
http://dx.doi.org/10.1038/s12276-023-00950-0

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