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Investigating the potential anti-depressive mechanisms of statins: a transcriptomic and Mendelian randomization analysis

Observational studies and randomized controlled trials presented inconsistent findings on the effects of cholesterol-lowering statins on depression. It therefore remains unclear whether statins have any beneficial effects on depression, and if so, what the underlying molecular mechanisms are. Here,...

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Detalles Bibliográficos
Autores principales: Jiang, Jiayue-Clara, Hu, Chenwen, McIntosh, Andrew M., Shah, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073189/
https://www.ncbi.nlm.nih.gov/pubmed/37015906
http://dx.doi.org/10.1038/s41398-023-02403-8