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De novo birth of functional microproteins in the human lineage

Small open reading frames (sORFs) can encode functional “microproteins” that perform crucial biological tasks. However, their size makes them less amenable to genomic analysis, and their origins and conservation are poorly understood. Given their short length, it is plausible that some of these func...

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Detalles Bibliográficos
Autores principales: Vakirlis, Nikolaos, Vance, Zoe, Duggan, Kate M., McLysaght, Aoife
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073203/
https://www.ncbi.nlm.nih.gov/pubmed/36543139
http://dx.doi.org/10.1016/j.celrep.2022.111808