Cargando…
De novo birth of functional microproteins in the human lineage
Small open reading frames (sORFs) can encode functional “microproteins” that perform crucial biological tasks. However, their size makes them less amenable to genomic analysis, and their origins and conservation are poorly understood. Given their short length, it is plausible that some of these func...
Autores principales: | Vakirlis, Nikolaos, Vance, Zoe, Duggan, Kate M., McLysaght, Aoife |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073203/ https://www.ncbi.nlm.nih.gov/pubmed/36543139 http://dx.doi.org/10.1016/j.celrep.2022.111808 |
Ejemplares similares
-
De Novo Genes Arise at a Slow but Steady Rate along the Primate Lineage and Have Been Subject to Incomplete Lineage Sorting
por: Guerzoni, Daniele, et al.
Publicado: (2016) -
De Novo Origins of Human Genes
por: Guerzoni, Daniele, et al.
Publicado: (2011) -
Synteny-based analyses indicate that sequence divergence is not the main source of orphan genes
por: Vakirlis, Nikolaos, et al.
Publicado: (2020) -
Ohnologs and SSD Paralogs Differ in Genomic and Expression Features Related to Dosage Constraints
por: Vance, Zoe, et al.
Publicado: (2023) -
De Novo Origin of Protein-Coding Genes in Murine Rodents
por: Murphy, Daniel N., et al.
Publicado: (2012)