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A small RNA-guided PRC2 complex eliminates DNA as an extreme form of transposon silencing

In animal germlines, transposons are silenced at the transcriptional or post-transcriptional level to prevent deleterious expression. Ciliates employ a more direct approach by physically eliminating transposons from their soma, utilizing piRNAs to recognize transposons and imprecisely excise them. A...

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Detalles Bibliográficos
Autores principales: Wang, Chundi, Solberg, Therese, Maurer-Alcalá‬, Xyrus X., Swart, Estienne C., Gao, Feng, Nowacki, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073204/
https://www.ncbi.nlm.nih.gov/pubmed/36001962
http://dx.doi.org/10.1016/j.celrep.2022.111263