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A small RNA-guided PRC2 complex eliminates DNA as an extreme form of transposon silencing
In animal germlines, transposons are silenced at the transcriptional or post-transcriptional level to prevent deleterious expression. Ciliates employ a more direct approach by physically eliminating transposons from their soma, utilizing piRNAs to recognize transposons and imprecisely excise them. A...
Autores principales: | Wang, Chundi, Solberg, Therese, Maurer-Alcalá, Xyrus X., Swart, Estienne C., Gao, Feng, Nowacki, Mariusz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073204/ https://www.ncbi.nlm.nih.gov/pubmed/36001962 http://dx.doi.org/10.1016/j.celrep.2022.111263 |
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