Parallel recovery of chromatin accessibility and gene expression dynamics from frozen human regulatory T cells

Epigenetic features such as DNA accessibility dictate transcriptional regulation in a cell type- and cell state- specific manner, and mapping this in health vs. disease in clinically relevant material is opening the door to new mechanistic insights and new targets for therapy. Assay for Transposase...

Descripción completa

Detalles Bibliográficos
Autores principales: Wong, Ying Y., Harbison, Jessica E., Hope, Christopher M., Gundsambuu, Batjargal, Brown, Katherine A., Wong, Soon W., Brown, Cheryl Y, Couper, Jennifer J., Breen, Jimmy, Liu, Ning, Pederson, Stephen M., Köhne, Maren, Klee, Kathrin, Schultze, Joachim, Beyer, Marc, Sadlon, Timothy, Barry, Simon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073253/
https://www.ncbi.nlm.nih.gov/pubmed/37016052
http://dx.doi.org/10.1038/s41598-023-32256-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073253/
https://www.ncbi.nlm.nih.gov/pubmed/37016052
http://dx.doi.org/10.1038/s41598-023-32256-6

Ejemplares similares