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Lynch syndrome cancer vaccines: A roadmap for the development of precision immunoprevention strategies

Hereditary cancer syndromes (HCS) account for 5~10% of all cancer diagnosis. Lynch syndrome (LS) is one of the most common HCS, caused by germline mutations in the DNA mismatch repair (MMR) genes. Even with prospective cancer surveillance, LS is associated with up to 50% lifetime risk of colorectal,...

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Detalles Bibliográficos
Autores principales: Sei, Shizuko, Ahadova, Aysel, Keskin, Derin B., Bohaumilitzky, Lena, Gebert, Johannes, von Knebel Doeberitz, Magnus, Lipkin, Steven M., Kloor, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073468/
https://www.ncbi.nlm.nih.gov/pubmed/37035178
http://dx.doi.org/10.3389/fonc.2023.1147590