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Pharmacokinetic comparison of sitagliptin and metformin HCl extended-release tablets versus JANUMET(®) XR in healthy volunteers under fasting and fed conditions

Background and Objectives: Janumet(®) XR is the combination of sitagliptin and extended metformin hydrochloride produced by Merck Sharp & Dohme. It is specially designed for diabetes mellitus patients taking both drugs already. Janumet(®) XR exhibited clinically significant blood glucose lowerin...

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Detalles Bibliográficos
Autores principales: Que, Linling, Qin, Wei, Shi, Yunfei, Ding, Ying, Huang, Kai, Qian, Zhenzhong, Huang, Bingjie, Zhou, Peipei, He, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073488/
https://www.ncbi.nlm.nih.gov/pubmed/37033652
http://dx.doi.org/10.3389/fphar.2023.1105767