Reactive oxygen species-responsive HET0016 prodrug-loaded liposomes attenuate neuroinflammation and improve neurological deficit in a rat model of juvenile traumatic brain injury

The arachidonic acid pathway metabolite 20-hydroxyeicosatetraenoic acid (20-HETE) contributes to ischemia/reperfusion brain injury. Inhibition of 20-HETE formation can protect the developing brain from global ischemia. In previous studies, we have found that treatment with the 20-HETE synthesis inhi...

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Detalles Bibliográficos
Autores principales: Qin, Jun, Chen, Xiaoli, Wang, Rui, Tian, Zedan, Li, Yang, Shu, Shiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073507/
https://www.ncbi.nlm.nih.gov/pubmed/37034179
http://dx.doi.org/10.3389/fnins.2023.1153349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073507/
https://www.ncbi.nlm.nih.gov/pubmed/37034179
http://dx.doi.org/10.3389/fnins.2023.1153349

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