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Helicobacter pylori-induced aberrant demethylation and expression of GNB4 promotes gastric carcinogenesis via the Hippo–YAP1 pathway

BACKGROUND: Helicobacter pylori (H. pylori) infection causes aberrant DNA methylation and contributes to the risk of gastric cancer (GC). Guanine nucleotide-binding protein subunit beta-4 (GNB4) is involved in various tumorigenic processes. We found an aberrant methylation level of GNB4 in H. pylori...

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Detalles Bibliográficos
Autores principales: Liu, Duanrui, Liu, Yunyun, Zhu, Wenshuai, Lu, Yi, Zhu, Jingyu, Ma, Xiaoli, Xing, Yuanxin, Yuan, Mingjie, Ning, Bin, Wang, Yunshan, Jia, Yanfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073623/
https://www.ncbi.nlm.nih.gov/pubmed/37016382
http://dx.doi.org/10.1186/s12916-023-02842-6