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P2Y(11)/IL-1 receptor crosstalk controls macrophage inflammation: a novel target for anti-inflammatory strategies?

Although first cloning of the human ATP receptor P2Y(11) was successful 25 years ago, the exact downstream signaling pathways of P2Y(11) receptor, which can couple to G(q) and G(s) proteins, have remained unclear. Especially the lack of rodent models as well as the limited availability of antibodies...

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Detalles Bibliográficos
Autores principales: Klaver, Dominik, Thurnher, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073626/
https://www.ncbi.nlm.nih.gov/pubmed/37016172
http://dx.doi.org/10.1007/s11302-023-09932-3