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Unwinding the mechanism of macrophage repolarization potential of Oceanimonas sp. BPMS22-derived protein protease inhibitor through Toll-like receptor 4 against experimental visceral leishmaniasis

The Oceanimonas sp. BPMS22-derived protein protease inhibitor (PPI) has been proven to shift macrophages towards an inflammatory state and reduce Leishmania donovani infection in vitro and in vivo. The current study explored and validated the mechanistic aspects of the PPI and Toll-like receptor (TL...

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Detalles Bibliográficos
Autores principales: Jayaraman, Adithyan, Srinivasan, Sujatha, Uppuluri, Kiran Babu, Kar Mahapatra, Santanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073655/
https://www.ncbi.nlm.nih.gov/pubmed/37033485
http://dx.doi.org/10.3389/fcimb.2023.1120888