Longitudinal home-cage automated assessment of climbing behavior shows sexual dimorphism and aging-related decrease in C57BL/6J healthy mice and allows early detection of motor impairment in the N171-82Q mouse model of Huntington’s disease

Monitoring the activity of mice within their home cage is proving to be a powerful tool for revealing subtle and early-onset phenotypes in mouse models. Video-tracking, in particular, lends itself to automated machine-learning technologies that have the potential to improve the manual annotations ca...

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Detalles Bibliográficos
Autores principales: Bains, Rasneer S., Forrest, Hamish, Sillito, Rowland R., Armstrong, J. Douglas, Stewart, Michelle, Nolan, Patrick M., Wells, Sara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Behavioral Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073658/
https://www.ncbi.nlm.nih.gov/pubmed/37035623
http://dx.doi.org/10.3389/fnbeh.2023.1148172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073658/
https://www.ncbi.nlm.nih.gov/pubmed/37035623
http://dx.doi.org/10.3389/fnbeh.2023.1148172

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