The integrated single-cell analysis developed a lactate metabolism-driven signature to improve outcomes and immunotherapy in lung adenocarcinoma

BACKGROUND: It has been suggested that lactate metabolism (LM) is crucial for the development of cancer. Using integrated single-cell RNA sequencing (scRNA-seq) analysis, we built predictive models based on LM-related genes (LMRGs) to propose novel targets for the treatment of LUAD patients. METHODS...

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Detalles Bibliográficos
Autores principales: Zhang, Pengpeng, Pei, Shengbin, Gong, Zeitian, Ren, Qianhe, Xie, Jiaheng, Liu, Hong, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073691/
https://www.ncbi.nlm.nih.gov/pubmed/37033259
http://dx.doi.org/10.3389/fendo.2023.1154410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073691/
https://www.ncbi.nlm.nih.gov/pubmed/37033259
http://dx.doi.org/10.3389/fendo.2023.1154410

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