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The integrated single-cell analysis developed a lactate metabolism-driven signature to improve outcomes and immunotherapy in lung adenocarcinoma
BACKGROUND: It has been suggested that lactate metabolism (LM) is crucial for the development of cancer. Using integrated single-cell RNA sequencing (scRNA-seq) analysis, we built predictive models based on LM-related genes (LMRGs) to propose novel targets for the treatment of LUAD patients. METHODS...
Autores principales: | Zhang, Pengpeng, Pei, Shengbin, Gong, Zeitian, Ren, Qianhe, Xie, Jiaheng, Liu, Hong, Wang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073691/ https://www.ncbi.nlm.nih.gov/pubmed/37033259 http://dx.doi.org/10.3389/fendo.2023.1154410 |
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