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HZ-A-018, a novel inhibitor of Bruton tyrosine kinase, exerts anti-cancer activity and sensitizes 5-FU in gastric cancer cells

Gastric cancer is the third leading cause of cancer related death worldwide. Due to the complexity and heterogeneity of gastric cancer, the development of targeted drugs is somehow limited, but is urgently needed. Since the expression of Bruton tyrosine kinase (BTK) was significantly associated with...

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Detalles Bibliográficos
Autores principales: Liu, Danjing, Xu, Wei, Lin, Bin, Ji, Cong, Shen, Minmin, Shen, Shuying, Ma, Junjie, Zhou, Xinglu, Yan, Youyou, Zhang, Bo, Lin, Nengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073700/
https://www.ncbi.nlm.nih.gov/pubmed/37033615
http://dx.doi.org/10.3389/fphar.2023.1142127