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Ultra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated tau

Autopsy data indicate that the locus coeruleus (LC) is one of the first sites in the brain to accumulate hyperphosphorylated tau pathology, with the rostral part possibly being more vulnerable in the earlier stages of the disease. Taking advantage of recent developments in ultra-high field (7 T) ima...

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Detalles Bibliográficos
Autores principales: Van Egroo, Maxime, Riphagen, Joost M., Ashton, Nicholas J., Janelidze, Shorena, Sperling, Reisa A., Johnson, Keith A., Yang, Hyun-Sik, Bennett, David A., Blennow, Kaj, Hansson, Oskar, Zetterberg, Henrik, Jacobs, Heidi I. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073793/
https://www.ncbi.nlm.nih.gov/pubmed/37020050
http://dx.doi.org/10.1038/s41380-023-02041-y