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5'‑isomiR is the most abundant sequence of miR‑1246, a candidate biomarker of lung cancer, in serum
MicroRNA (miRNA/miR) 5′-isoforms (5′-isomiRs) differ from canonical sequences registered in the microRNA database in the length of their 5′ ends. The ‘seed sequence’ of miRNAs that bind to target mRNAs is 2–8 nucleotides from the 5′ end; thus, shifts at the 5′ end can cause a ‘seed shift’. Accumulat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073804/ https://www.ncbi.nlm.nih.gov/pubmed/36960865 http://dx.doi.org/10.3892/mmr.2023.12979 |