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Patients’ IgLON5 autoantibodies interfere with IgLON5-protein interactions

BACKGROUND: Anti-IgLON5 disease is a rare neurological disorder characterized by autoantibodies against IgLON5, and pathological evidence of neurodegeneration. IgLON5 is a cell adhesion molecule but its physiological function is unknown. Our aim was to investigate the IgLON5 interactome and to deter...

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Detalles Bibliográficos
Autores principales: Landa, Jon, Serafim, Ana Beatriz, Gaig, Carles, Saiz, Albert, Koneczny, Inga, Hoftberger, Romana, Santamaria, Joan, Dalmau, Josep, Graus, Francesc, Sabater, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073962/
https://www.ncbi.nlm.nih.gov/pubmed/37033996
http://dx.doi.org/10.3389/fimmu.2023.1151574