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Motif elucidation in ChIP-seq datasets with a knockout control
SUMMARY: Chromatin immunoprecipitation-sequencing is widely used to find transcription factor binding sites, but suffers from various sources of noise. Knocking out the target factor mitigates noise by acting as a negative control. Paired wild-type and knockout (KO) experiments can generate improved...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074035/ https://www.ncbi.nlm.nih.gov/pubmed/37033469 http://dx.doi.org/10.1093/bioadv/vbad031 |